BIOFILME E A PATOGÊNESE DAS LESÕES PERIRRADICULARES
Palabras clave:
Infecção endodôntica, Biofilme, Lesões perirradiculares, Patogenicidade bacteriana
Resumen
O controle de uma infecção endodôntica demanda um esforço concentrado de fatores gerais do hospedeiro e de medidas de tratamento a partir da compreensão da etiologia e patogênese das doenças endodônticas. Atualmente há uma tendência de se considerar as lesões perirradiculares como doença induzida por biofilme. Este artigo de revisão tem como objetivo apresentar o biofilme dentro do conceito de comunidade como unidade de patogenicidade. O conhecimento e a compreensão do conceito de comunidade são importantes, pois o aprimoramento do endodontista no campo da microbiologia é fundamental para o entendimento do processo infeccioso que se propõe a eliminar. Isto se justifica para poder elaborar estratégias que permitam tratar de forma previsível o dente acometido.
[Vieira MVB, Moreno JO, Lopes WSP, Martínez AM. Biofilme e a patogênese das lesões perriradiculares. Ustasalud 2011; 10: 60 - 64]
Referencias
1. Siqueira JF Jr, Rôças, IN, Lopes HP. Microbiologia endodôntica. In: Endodontia: biologia e técnica. 3. Ed. Rio de Janeiro: Guanabara Koogan; 2010. p. 103-146.
2. Siqueira JF Jr, Rôças, IN. Community as the unit of the pathogenicity: An emerging concept as to the microbial pathogenesis of the apical periodontitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107: 870 - 878.
3. Haapasalo M, Endal U. Control and elimination of endodontic infection. Roots 2006;1: 15 - 22.
4. Alves FRF. Compreendendo a etiologia das infecções endodônticas. Rev Biociên 2004;10: 67 - 71.
5. Siqueira JF Jr. Reaction of perirradicular tissues to root canal treatment: benefits and drawbacks. Endod Topics 2005; 10: 123 – 147.
6. Siqueira JF Jr, RôçaS, IN. Distinctive features of the microbiota associated with different forms of apical periodontitis. J Oral Microbiol 2009; 1.
7. Siqueira JF Jr. Treatment of Endodontic Infections. London: Quintessence Publishing, 2011.
8. Parsek MR, Greenberg EP. Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol 2005; 13: 27 - 33.
9. Blome B Braun A, Sobarzo V. Jepsen S. Molecular identification and quantification of bacteria from endodontic infections using real-time polymerase chain reaction. Oral Microbiol Immunol 2008; 23: 384 - 390.
10. Rôças IN, Siqueira JF Jr, Aboim MC, Rosado AS. Denaturing gradiente gel electrophoresis analysis of bacterial communities associated with failed endodontics treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 741 - 749.
11. Rôças IN, Hulsmann M, Siqueira JF Jr. Microorganisms in root canal-treated teeth from a German population. J Endod 2008; 34: 926 - 931.
12. Sakamoto M, Siqueira JF Jr, Rôças IN, Benno Y. Molecular analysis of the root canal microbiota associated with endodontic treatment failures. Oral Microbiol Immunol 2008; 23: 275 - 281.
13. Siqueira JF Jr, Rôças IN. Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 97: 85 - 94.
14. Costerton JW. The biofilm primer. Berlim: Heidelberg: Springer-Verlag, 2007.
15. Kuramitsu HK, He X, Lux R. Anderson MH, Shi W. Interspecies interactions within oral microbial communities. Microbiol Mol Biol Rev 2007; 71: 653 - 670.
16. Marsh PD. Are dental diseases examples of ecological catastrophes? Microbiology 2003; 149: 279 - 294.
17. Donlan RM, Costerton JW. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 2002; 15: 167 -193.
18. Hall-stoodley L, Costerton JW, Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2004; 2: 95 - 108.
19. Marsh PD. Dental plaque as a microbial biofilm. Caries Res 2004; 38: 204 – 211.
20. Schaudinm C, Gorur A, Keller D, Sedqhizadeh PP, Costerton JW. Periodontitis: An archetypical biofilm disease. J Am Dent Assoc 2009; 140: 978 - 986.
21. Hall-stoodley L, Stoodley P. Evolving concepts in biofilm infections. Cell Microbiol 2009; 11: 1034 - 1043.
22. Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science 1999; 284: 1318 - 1322.
23. Socransky SS, Haffajjee AD. Dental biofilms: difficult therapeutic targets. Periodontol 2000 2002; 28: 12 – 55.
24. Stoodley P, Sauer K, Davies DG. Biofilms as complex differentiated communities. Annu Rev Microbiol 2002; 56: 187 - 209.
25. Costerton B. Microbiol ecology comes of age and joins the general ecology community. Proc Natl Acad Sci USAv 2004; 101: 16983 - 16984.
26. Chavez de Paz L. Redefining the persistent infection in root canals: possible role of biofilm communities. J Endod 2007; 33: 652 - 662.
27. Svensäter G, Bergenholtz G. Biofilms in endodontic infections. Endod Topics 2004; 9:27 - 36.
28. Ricucci D, Siqueira JF Jr. Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings. J Endod 2010; 36: 1277 - 1288.
29. Tronstad L, Sunde PT. The evolving new understanding of endodontic infections. Endod Topics 2003; 6: 57 - 77.
30. Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surg Oral Med Oral Pathol 1965; 20: 340 - 349.
31. Möller AJ. R, Fabricius L, Dahlén G. Ohman AE, Heyden G. Influence on periapical tissues of indigenous oral bacteria and necrotic pulp tissue in monkeys. Scand J Dent Res 1981; 89: 475 – 484.
32. Sundqvist G. Bacteriological studies of necrotic dental pulps [Dissertation]. Umea Sweden: University of Umea; 1976.
33. Siqueira JF Jr, Rôças IN. Bacterial pathogenesis and mediators in apical periodontitis. Braz Dent J 2007; 18: 267 – 280.
34. Beloin C, Valle J, Latour – Lambert P, Faure P, Kzreminski M, Balestrino D, et al. Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression. Mol Microbiol 2004; 51: 659 – 674.
35. Brady RA, Leid JG, Calhoun JH, Costerton JW, Shirtliff ME. Osteomyelitis and the role of biofilms in chronic infection. FEMS Immunol Med Microbiol 2008; 52: 3 – 22.
36. Costerton JW, Veeh R, Shirtliff M, Pasmore M, Post C, Ehrlich G. The applications of biofilm science to the study and control of chronic bacterial infections. J Clin Invest 2003; 112: 1666 – 1477.
37. Furukawa S, Kuchma SL, O’Toole GA. Keeping their options open: acute versus persistent infections. J Bacteriol 2006; 188: 1211 - 1217
38. Sauer K., Camper AK, Ehrlich GD, Costerton JW, Davies DG. Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm. J Bacteriol 2002; 184: 1140 – 1154.
2. Siqueira JF Jr, Rôças, IN. Community as the unit of the pathogenicity: An emerging concept as to the microbial pathogenesis of the apical periodontitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107: 870 - 878.
3. Haapasalo M, Endal U. Control and elimination of endodontic infection. Roots 2006;1: 15 - 22.
4. Alves FRF. Compreendendo a etiologia das infecções endodônticas. Rev Biociên 2004;10: 67 - 71.
5. Siqueira JF Jr. Reaction of perirradicular tissues to root canal treatment: benefits and drawbacks. Endod Topics 2005; 10: 123 – 147.
6. Siqueira JF Jr, RôçaS, IN. Distinctive features of the microbiota associated with different forms of apical periodontitis. J Oral Microbiol 2009; 1.
7. Siqueira JF Jr. Treatment of Endodontic Infections. London: Quintessence Publishing, 2011.
8. Parsek MR, Greenberg EP. Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol 2005; 13: 27 - 33.
9. Blome B Braun A, Sobarzo V. Jepsen S. Molecular identification and quantification of bacteria from endodontic infections using real-time polymerase chain reaction. Oral Microbiol Immunol 2008; 23: 384 - 390.
10. Rôças IN, Siqueira JF Jr, Aboim MC, Rosado AS. Denaturing gradiente gel electrophoresis analysis of bacterial communities associated with failed endodontics treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98: 741 - 749.
11. Rôças IN, Hulsmann M, Siqueira JF Jr. Microorganisms in root canal-treated teeth from a German population. J Endod 2008; 34: 926 - 931.
12. Sakamoto M, Siqueira JF Jr, Rôças IN, Benno Y. Molecular analysis of the root canal microbiota associated with endodontic treatment failures. Oral Microbiol Immunol 2008; 23: 275 - 281.
13. Siqueira JF Jr, Rôças IN. Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 97: 85 - 94.
14. Costerton JW. The biofilm primer. Berlim: Heidelberg: Springer-Verlag, 2007.
15. Kuramitsu HK, He X, Lux R. Anderson MH, Shi W. Interspecies interactions within oral microbial communities. Microbiol Mol Biol Rev 2007; 71: 653 - 670.
16. Marsh PD. Are dental diseases examples of ecological catastrophes? Microbiology 2003; 149: 279 - 294.
17. Donlan RM, Costerton JW. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 2002; 15: 167 -193.
18. Hall-stoodley L, Costerton JW, Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2004; 2: 95 - 108.
19. Marsh PD. Dental plaque as a microbial biofilm. Caries Res 2004; 38: 204 – 211.
20. Schaudinm C, Gorur A, Keller D, Sedqhizadeh PP, Costerton JW. Periodontitis: An archetypical biofilm disease. J Am Dent Assoc 2009; 140: 978 - 986.
21. Hall-stoodley L, Stoodley P. Evolving concepts in biofilm infections. Cell Microbiol 2009; 11: 1034 - 1043.
22. Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: a common cause of persistent infections. Science 1999; 284: 1318 - 1322.
23. Socransky SS, Haffajjee AD. Dental biofilms: difficult therapeutic targets. Periodontol 2000 2002; 28: 12 – 55.
24. Stoodley P, Sauer K, Davies DG. Biofilms as complex differentiated communities. Annu Rev Microbiol 2002; 56: 187 - 209.
25. Costerton B. Microbiol ecology comes of age and joins the general ecology community. Proc Natl Acad Sci USAv 2004; 101: 16983 - 16984.
26. Chavez de Paz L. Redefining the persistent infection in root canals: possible role of biofilm communities. J Endod 2007; 33: 652 - 662.
27. Svensäter G, Bergenholtz G. Biofilms in endodontic infections. Endod Topics 2004; 9:27 - 36.
28. Ricucci D, Siqueira JF Jr. Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings. J Endod 2010; 36: 1277 - 1288.
29. Tronstad L, Sunde PT. The evolving new understanding of endodontic infections. Endod Topics 2003; 6: 57 - 77.
30. Kakehashi S, Stanley HR, Fitzgerald RJ. The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surg Oral Med Oral Pathol 1965; 20: 340 - 349.
31. Möller AJ. R, Fabricius L, Dahlén G. Ohman AE, Heyden G. Influence on periapical tissues of indigenous oral bacteria and necrotic pulp tissue in monkeys. Scand J Dent Res 1981; 89: 475 – 484.
32. Sundqvist G. Bacteriological studies of necrotic dental pulps [Dissertation]. Umea Sweden: University of Umea; 1976.
33. Siqueira JF Jr, Rôças IN. Bacterial pathogenesis and mediators in apical periodontitis. Braz Dent J 2007; 18: 267 – 280.
34. Beloin C, Valle J, Latour – Lambert P, Faure P, Kzreminski M, Balestrino D, et al. Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression. Mol Microbiol 2004; 51: 659 – 674.
35. Brady RA, Leid JG, Calhoun JH, Costerton JW, Shirtliff ME. Osteomyelitis and the role of biofilms in chronic infection. FEMS Immunol Med Microbiol 2008; 52: 3 – 22.
36. Costerton JW, Veeh R, Shirtliff M, Pasmore M, Post C, Ehrlich G. The applications of biofilm science to the study and control of chronic bacterial infections. J Clin Invest 2003; 112: 1666 – 1477.
37. Furukawa S, Kuchma SL, O’Toole GA. Keeping their options open: acute versus persistent infections. J Bacteriol 2006; 188: 1211 - 1217
38. Sauer K., Camper AK, Ehrlich GD, Costerton JW, Davies DG. Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm. J Bacteriol 2002; 184: 1140 – 1154.
Publicado
2011-01-01
Cómo citar
Boussada Vieira, M., Moreno Monsalve, J., Pereira Lopes, W., & Martínez Santamaría, Ángela. (2011). BIOFILME E A PATOGÊNESE DAS LESÕES PERIRRADICULARES. Ustasalud, 10(1), 60 - 64. https://doi.org/https://doi.org/10.15332/us.v10i1.1152
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Sección
Artículos de Revisión
